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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha : |
15/11/2023 |
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Actualizado : |
15/11/2023 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Autor : |
GARCÍA-ROCHE, M.; TALMÓN, D.; CAÑIBE, G.; ASTESSIANO, A.L.; MENDOZA, A.; CASSINA, A.; QUIJANO, C.; CARRIQUIRY, M. |
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Afiliación : |
MERCEDES GARCÍA-ROCHE, Facultad de Agronomía, Dpto. Producción Animal y Pasturas, Universidad de la República, Montevideo, Uruguay; Facultad de Medicina, Centro de Investigaciones Biomédicas (CEINBIO), Dpto. Bioquímica, Universidad de la República, Montevideo; DANIEL TALMÓN, Facultad de Agronomía, Departamento de Producción Animal y Pasturas, Universidad de la República, Montevideo, Uruguay; GUILLERMO CAÑIBE, Facultad de Agronomía, Departamento de Producción Animal y Pasturas, Universidad de la República, Montevideo, Uruguay; ANAL LAURA ASTESSIANO, Facultad de Agronomía, Departamento de Producción Animal y Pasturas, Universidad de la República, Montevideo, Uruguay; ALEJANDRO FRANCISCO MENDOZA AGUIAR, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; ADRIANA CASSINA, Facultad de Medicina, Centro de Investigaciones Biomédicas (CEINBIO), Departamento de Bioquímica, Universidad de la República, Montevideo, Uruguay; CELIA QUIJANO, Facultad de Medicina, Centro de Investigaciones Biomédicas (CEINBIO), Departamento de Bioquímica, Universidad de la República, Montevideo, Uruguay; MARIANA CARRIQUIRY, Facultad de Agronomía, Departamento de Producción Animal y Pasturas, Universidad de la República, Montevideo, Uruguay. |
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Título : |
Hepatic metabolism of grazing cows of two Holstein strains under two feeding strategies with different levels of pasture inclusion. |
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Fecha de publicación : |
2023 |
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Fuente / Imprenta : |
PLoS ONE, October 2023, Volume 18, Issue 10, e0290551. https://doi.org/10.1371/journal.pone.0290551 -- OPEN ACCESS. |
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ISSN : |
1932-6203 |
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DOI : |
10.1371/journal.pone.0290551 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received March 22 2023; Accepted August 9 2023; Published October 26 2023. -- Correspondence: García-Roche, M.; Facultad de Agronomía, Departamento de Producción Animal y Pasturas, Universidad de la República, Montevideo, Uruguay; email:mercedesg@fagro.edu.uy --
Editor: Arda Yildirim, Tokat Gaziosmanpasa University: Tokat Gaziosmanpasa Universitesi, TURKEY. -- FUNDING: M. García-Roche was supported by Comisión Académica de Posgrados - Universidad de la República fellowship BDDX_2018_1#49004502. D. Talmón was supported by Agencia Nacional de Investigación e Innovación (ANII) fellowship POS_NAC_2017_1_141266. A. Cassina and C. Quijano were funded by grants of the Espacio Interdisciplinario - Centros, Universidad de la República 2015 and Comisión Sectorial de Investigación Científica (CSIC) grupos I+D 2022 (22620220100012UD). A. Cassina was also supported by the grant Comisión Sectorial de Investigación Científica (CSIC) grupos I+D 2014 (767). The project was funded by Comisión Sectorial de Investigación Científica (CSIC) of the Universidad de la República CSIC I+D 2018 ID 103 to M. Carriquiry and C. Quijano as well as by Agencia Nacional de Investigación e Innovación INNOVAGRO 2018: FSA_1_2018_1_152220 to M. Carriquiry and A. Cassina. A. Mendoza received funding from the project PL_21_0_00 of Instituto Nacional de Investigación Agropecuaria. -- Data Availability: All relevant data are within the paper and its Supporting Information files (https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0290551#sec023 ). -- Document type: Article Gold Open Access. -- LICENSE: This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ ). -- |
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Contenido : |
ABSTRACT.- The objective of the study was to characterize adaptations of hepatic metabolism of dairy cows of two Holstein strains with varying proportions of grazing in the feeding strategy. Multiparous autumn calving Holstein cows of New Zealand (NZH) and North American (NAH) strains were assigned to a randomized complete block design with a 2 x 2 factorial arrangement with two feeding strategies that varied in the proportions of pasture and supplementation: maximum pasture and supplementation with a pelleted concentrate (MaxP) or fixed pasture and supplementation with a total mixed ration (FixP) from May through November of 2018. Hepatic biopsies were taken at - 45 ± 17, 21 ± 7, 100 ± 23 and 180 ± 23 days in milk (DIM), representing prepartum, early lactation, early mid-lactation and late mid-lactation. The effects of DIM, feeding strategy (FS), strain and their interactions were analyzed with mixed models using repeated measures. Cows of both strains had similar triglyceride levels, mitochondrial function and carnitine palmitoyltransferase activity in liver during lactation. However, there was an effect of DIM and FS as liver triglyceride was higher for the MaxP strategy at 21 DIM and both mitochondrial function and carnitine palmitoyltransferase activity in liver were lower for the MaxP strategy at 21 DIM. Hepatic mitochondrial function and acetylation levels were affected by the interaction between strain and feeding strategy as both variables were higher for NAH cows in the MaxP strategy. Mid-lactation hepatic gene expression of enzymes related to fatty acid metabolism and nuclear receptors was higher for NZH than NAH cows. This work confirms the association between liver triglyceride, decreased hepatic mitochondrial function and greater mitochondrial acetylation levels in cows with a higher inclusion of pasture and suggests differential adaptative mechanisms between NAH and NZH cows to strategies with varying proportions of grazing in the feeding strategy. Copyright: © 2023 García-Roche et al. MenosABSTRACT.- The objective of the study was to characterize adaptations of hepatic metabolism of dairy cows of two Holstein strains with varying proportions of grazing in the feeding strategy. Multiparous autumn calving Holstein cows of New Zealand (NZH) and North American (NAH) strains were assigned to a randomized complete block design with a 2 x 2 factorial arrangement with two feeding strategies that varied in the proportions of pasture and supplementation: maximum pasture and supplementation with a pelleted concentrate (MaxP) or fixed pasture and supplementation with a total mixed ration (FixP) from May through November of 2018. Hepatic biopsies were taken at - 45 ± 17, 21 ± 7, 100 ± 23 and 180 ± 23 days in milk (DIM), representing prepartum, early lactation, early mid-lactation and late mid-lactation. The effects of DIM, feeding strategy (FS), strain and their interactions were analyzed with mixed models using repeated measures. Cows of both strains had similar triglyceride levels, mitochondrial function and carnitine palmitoyltransferase activity in liver during lactation. However, there was an effect of DIM and FS as liver triglyceride was higher for the MaxP strategy at 21 DIM and both mitochondrial function and carnitine palmitoyltransferase activity in liver were lower for the MaxP strategy at 21 DIM. Hepatic mitochondrial function and acetylation levels were affected by the interaction between strain and feeding strategy as both variables were higher for NAH cows i... Presentar Todo |
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Palabras claves : |
Animals; Carnitine O-Palmitoyltransferase; Cattle; Diet; Dietary Supplements; SISTEMA LECHERO - INIA. |
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Asunto categoría : |
L01 Ganadería |
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URL : |
https://doi.org/10.1371/journal.pone.0290551
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Marc : |
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001 1064371
005 2023-11-15
008 2023 bl uuuu u00u1 u #d
022 $a1932-6203
024 7 $a10.1371/journal.pone.0290551$2DOI
100 1 $aGARCÍA-ROCHE, M.
245 $aHepatic metabolism of grazing cows of two Holstein strains under two feeding strategies with different levels of pasture inclusion.$h[electronic resource]
260 $c2023
500 $aArticle history: Received March 22 2023; Accepted August 9 2023; Published October 26 2023. -- Correspondence: García-Roche, M.; Facultad de Agronomía, Departamento de Producción Animal y Pasturas, Universidad de la República, Montevideo, Uruguay; email:mercedesg@fagro.edu.uy -- Editor: Arda Yildirim, Tokat Gaziosmanpasa University: Tokat Gaziosmanpasa Universitesi, TURKEY. -- FUNDING: M. García-Roche was supported by Comisión Académica de Posgrados - Universidad de la República fellowship BDDX_2018_1#49004502. D. Talmón was supported by Agencia Nacional de Investigación e Innovación (ANII) fellowship POS_NAC_2017_1_141266. A. Cassina and C. Quijano were funded by grants of the Espacio Interdisciplinario - Centros, Universidad de la República 2015 and Comisión Sectorial de Investigación Científica (CSIC) grupos I+D 2022 (22620220100012UD). A. Cassina was also supported by the grant Comisión Sectorial de Investigación Científica (CSIC) grupos I+D 2014 (767). The project was funded by Comisión Sectorial de Investigación Científica (CSIC) of the Universidad de la República CSIC I+D 2018 ID 103 to M. Carriquiry and C. Quijano as well as by Agencia Nacional de Investigación e Innovación INNOVAGRO 2018: FSA_1_2018_1_152220 to M. Carriquiry and A. Cassina. A. Mendoza received funding from the project PL_21_0_00 of Instituto Nacional de Investigación Agropecuaria. -- Data Availability: All relevant data are within the paper and its Supporting Information files (https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0290551#sec023 ). -- Document type: Article Gold Open Access. -- LICENSE: This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ ). --
520 $aABSTRACT.- The objective of the study was to characterize adaptations of hepatic metabolism of dairy cows of two Holstein strains with varying proportions of grazing in the feeding strategy. Multiparous autumn calving Holstein cows of New Zealand (NZH) and North American (NAH) strains were assigned to a randomized complete block design with a 2 x 2 factorial arrangement with two feeding strategies that varied in the proportions of pasture and supplementation: maximum pasture and supplementation with a pelleted concentrate (MaxP) or fixed pasture and supplementation with a total mixed ration (FixP) from May through November of 2018. Hepatic biopsies were taken at - 45 ± 17, 21 ± 7, 100 ± 23 and 180 ± 23 days in milk (DIM), representing prepartum, early lactation, early mid-lactation and late mid-lactation. The effects of DIM, feeding strategy (FS), strain and their interactions were analyzed with mixed models using repeated measures. Cows of both strains had similar triglyceride levels, mitochondrial function and carnitine palmitoyltransferase activity in liver during lactation. However, there was an effect of DIM and FS as liver triglyceride was higher for the MaxP strategy at 21 DIM and both mitochondrial function and carnitine palmitoyltransferase activity in liver were lower for the MaxP strategy at 21 DIM. Hepatic mitochondrial function and acetylation levels were affected by the interaction between strain and feeding strategy as both variables were higher for NAH cows in the MaxP strategy. Mid-lactation hepatic gene expression of enzymes related to fatty acid metabolism and nuclear receptors was higher for NZH than NAH cows. This work confirms the association between liver triglyceride, decreased hepatic mitochondrial function and greater mitochondrial acetylation levels in cows with a higher inclusion of pasture and suggests differential adaptative mechanisms between NAH and NZH cows to strategies with varying proportions of grazing in the feeding strategy. Copyright: © 2023 García-Roche et al.
653 $aAnimals
653 $aCarnitine O-Palmitoyltransferase
653 $aCattle
653 $aDiet
653 $aDietary Supplements
653 $aSISTEMA LECHERO - INIA
700 1 $aTALMÓN, D.
700 1 $aCAÑIBE, G.
700 1 $aASTESSIANO, A.L.
700 1 $aMENDOZA, A.
700 1 $aCASSINA, A.
700 1 $aQUIJANO, C.
700 1 $aCARRIQUIRY, M.
773 $tPLoS ONE, October 2023, Volume 18, Issue 10, e0290551. https://doi.org/10.1371/journal.pone.0290551 -- OPEN ACCESS.
Descargar
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Registro original : |
INIA Las Brujas (LB) |
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| Registros recuperados : 129 | |
| 61. |  | MONTOSSI, F.; LUZARDO, S.; CUADRO, R.; BRITO, G.; SAN JULIÁN, R.; SILVEIRA, C.; DEL CAMPO, M. The use of restricted grain supplementation to promote simultaneously beef production and healthy meat under grazing conditions. In: International Congress of Meat Science and Technology (ICoMST), 57o., 7-12 August, Ghent-Belgium, 2011. Poster session 8: Animal Nutrition effects on Meat Quality.| Tipo: Abstracts/Resúmenes |
| Biblioteca(s): INIA Tacuarembó. |
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| 63. | | MONTOSSI, F.; LUZARDO, S.; CUADRO, R.; BRITO, G.; SAN JULIÁN, R.; SILVEIRA, C.; DEL CAMPO, M. Could restricted grain supplementation modify fatty acid composition in beef meat under grazing conditions? In:International Congress of Meat Science and Technology (ICoMST), 56o., Corea, 2010. Abstracts session B: Meat and health.| Tipo: Abstracts/Resúmenes |
| Biblioteca(s): INIA Tacuarembó. |
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| 64. | | MONTOSSI, F.; LUZARDO, S.; CUADRO, R.; RISSO, D.; SAN JULIAN, R.; BRITO, G.; DE BARBIERI, I. Efecto de diferentes asignaciones de forraje y niveles de suplementación, en la performance animal, calidad de la canal y la carne de novillos Hereford. ln: INIA TACUAREMBÓ. INSTITUTO NACIONAL DE CARNES. Calidad de carnes. SEMINARIO DE ACTUALIZACIÓN TÉCNICA, 20-21 de setiembre, Tacuarembó, 2010. Montevideo (Uruguay): INIA, 2010.| Tipo: Trabajos en Congresos/Conferencias |
| Biblioteca(s): INIA Tacuarembó. |
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| 65. | | LUZARDO, S.; CUADRO, R.; MONTOSSI, F.; MEDEROS, A.; ALBERNAZ, F.; GONZÁLEZ, E.; PRESA, O.; LIMA, D.; COSTALES, J.; DE SOUZA, G.; ZAMIT, W.; BENTANCUR, M. Efecto del nivel de oferta de forraje y la suplementación energética otoño-invernal en una pastura permanente sobre la performance y calidad del producto de terneros y novillos Hereford. ln: INIA Tacuarembó. Unidad Experimental Glencoe. Día de campo, Glencoe, 10 setiembre 2010, Paysandú, Uruguay. Pasturas y producción animal. Tacuarembó (Uruguay): INIA, 2010. p. 13-16 (INIA Serie Actividades de Difusión ; 619)| Biblioteca(s): INIA Tacuarembó. |
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| 67. | | VIÑOLES, C.; CUADRO, R.; MÉNDEZ, R.; MARTÍN, A.; FERRÓN, M.; GUGGERI, D.; MOREIRA, E.; FRUGONI, J.C.; DE BARBIERI, I.; MONTOSSI, F. Impacto de la nutrición a edades tempranas sobre la pubertad y la preñez de terneras Hereford servidas a los 12-13 meses en sistemas ganaderos del basalto. ln: INIA Tacuarembó. Unidad Experimental Glencoe. Día de campo, Glencoe, 10 setiembre 2010, Paysandú, Uruguay. Pasturas y producción animal. Tacuarembó (Uruguay): INIA, 2010. p. 1-4 (INIA Serie Actividades de Difusión ; 619) Instituto Nacional de Investigación Agropecuaria (INIA)| Biblioteca(s): INIA Tacuarembó. |
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| 69. | | CUADRO, R. Sitio experimental Tambores. ln: INIA Tacuarembó. Gira Nacional de Pasturas Región Noreste y Norte, Tacuarembó. Tacuarembó (Uruguay): INIA, 2010. p. 20-24| Biblioteca(s): INIA Tacuarembó. |
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| 72. | | AYALA, W.; MONTOSSI, F.; BARRIOS, E.; BERMÚDEZ, R.; CUADRO, R.; LUZARDO, S.; SILVEIRA, C.; PÉREZ GOMAR, E.; PRAVIA, V.; ROVIRA, P.J.; VELAZCO, J.I. Summer forage feeding alternatives: opportunities and chalenges for pastoral systems in Uruguay. ln: Proceedings of the International Workshop to honor Prof. John Hodgson. An overview of research on pastoral - based systems in the southern part of South America: Tandil (Argentina):Universidad Nacional del Centro de la Provincia de Buenos Aires, 2010. p. 81-93| Tipo: Abstracts/Resúmenes |
| Biblioteca(s): INIA Treinta y Tres. |
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| 74. | | VIÑOLES, C.; GUGGERI, D.; CUADRO, P.; EGAÑA, J.; CUADRO, R.; MOREIRA, L.; RODRÍGUEZ, H.; SOARES DE LIMA, J.M.; MONTOSSI, F. Efecto de la alimentación pre-destete, la edad y el tipo de destete sobre el desarrollo corporal y el inicio de la pubertad en terneros Hereford. ln: INIA Tacuarembó. Unidad Experimental Glencoe. DÍA DE CAMPO, 10 setiembre, Paysandú, 2009. Producción Animal y Pasturas. Medidas de manejo y alimentación frente a eventos climáticos adversos. Lecciones aprendidas y propuestas a futuro. Tacuarembó (Uruguay): INIA, 2009. p. 9-12 (INIA Serie Actividades de Difusión ; 589)| Biblioteca(s): INIA Tacuarembó. |
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| 76. | | VIÑOLES, C.; GUGGERI, D.; EGAÑA, J.; CUADRO, P.; CUADRO, R.; MONTOSSI, F. Efecto del pastoreo sobre Ornithopus pinnatus a diferentes cargos sobre el reinicio de la actividad cíclica posparto en vacas de primera cría y la tasa de ganancia de los terneros. ln: INIA Tacuarembó. Unidad Experimental Glencoe. DÍA DE CAMPO, 10 setiembre, Paysandú, 2009. Producción Animal y Pasturas. Medidas de manejo y alimentación frente a eventos climáticos adversos. Lecciones aprendidas y propuestas a futuro. Tacuarembó (Uruguay): INIA, 2009. p. 7 (INIA Serie Actividades de Difusión ; 589)| Biblioteca(s): INIA Tacuarembó. |
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| 78. | | CUADRO, R.; PRESA, O.; SUÁREZ, M.; LIMA, D. Evaluación de verdeos de invierno. ln: INIA Tacuarembó. Unidad Experimental Glencoe. DÍA DE CAMPO, 10 setiembre, Paysandú, 2009. Producción Animal y Pasturas. Medidas de manejo y alimentación frente a eventos climáticos adversos. Lecciones aprendidas y propuestas a futuro. Tacuarembó (Uruguay): INIA, 2009. p. 1-4 (INIA Serie Actividades de Difusión ; 589)| Biblioteca(s): INIA Tacuarembó. |
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| 80. | | GIORELLO, D.; CUADRO, R. Nuevas forrajeras INIA: especies y variedades. Paso Farías, Artigas, 27 de agosto, 2009; Tacuarembó, 28 de agosto, 2009. ln: INIA TACUAREMBO. PROGRAMA NACIONAL DE INVESTIGACIÓN EN PRODUCCIÓN DE ARROZ. Presentación resultados experimentales de arroz Zafra 2008/2009. Tacuarembó (Uruguay): INIA, 2009. p. 108-110 (INIA Serie Actividades de Difusión ; 585)| Biblioteca(s): INIA Tacuarembó. |
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| Registros recuperados : 129 | |
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